ASCEplus® (ExoCoBio Inc)

EXOBALM-HR

Designed to be used overnight, this regenerative scalp treatment supports scalp balance, hydration, and healthier-looking hair. The formula is powered by ExoCoBio’s rose stem cell-derived extracellular vesicles technology, or RSCE™, which combines with growth factors, peptides, amino acids, and vitamins to help improve the scalp environment, addressing dry, stressed, or sensitive scalp conditions. To preserve the ingredients’ freshness, the formula is composed of two elements: a lyophilized Exocapsule® which contains approximately 2.5 billion purified extracellular vesicles with bioactive peptides, growth factors, amino acids, vitamins, and coenzymes; and a W-Formula™ balm activator which freshly reconstitutes the ingredients before use, for optimal stability and performance. To use, the two elements are mixed together, and the formula should be refrigerated and used within 21 days. In tests after four weeks of use, the product reduced hair shedding by 58%; improved scalp hydration by 29%; and scalp soothing parameters improved by 17%.

Hall (Pavilion) and Stand Number : #28222

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This product is a finalist in the category Hair Products of Cosmoprof North America 2026

Launch Date (First worldwide launch must have been launched within 12 months prior to the event). Date (Month/Day/Year)

11/12/2025

Retail Price & Fill Sizes

$120 / 20ml+20mg

Product Description (Function, Benefits, and Target Consumer)

Product Innovation

ASCEplus® EXOBALM-HR represents a new category in scalp care: a regenerative exosome-based overnight scalp cream inspired by professional aesthetic cosmetics. Unlike conventional hair products focused only on cosmetic appearance, EXOBALM-HR was developed to support the scalp microenvironment using ExoCoBio’s proprietary RSCE™ (Rose Stem Cell-Derived Extracellular Vesicles) technology. The product combines two advanced systems: 1. A lyophilized Exocapsule® containing approximately 2.5 billion purified extracellular vesicles with bioactive peptides, growth factors, amino acids, vitamins, and coenzymes. 2. A W-Formula™ balm activator designed to freshly reconstitute ingredients immediately before use for optimal stability and performance. This dual-chamber activation technology helps preserve ingredient integrity while maximizing freshness and biological activity at the moment of application. EXOBALM-HR was developed based on ExoCoBio’s clinical experience with ASCEplus® HRLV, a professional exosome scalp protocol used globally in regenerative aesthetic clinics. The formula was specifically designed as a home-use maintenance solution that complements professional procedures such as microneedling, laser treatments, and scalp recovery protocols.

Product Claims & Benefits

• Helps soothe stressed and sensitive scalp conditions • Helps improve scalp hydration and moisture balance • Helps reduce visible hair shedding • Supports healthier-looking, fuller-looking hair • Helps improve scalp comfort and reduce dryness • Supports scalp barrier recovery after aesthetic procedures • Helps improve scalp keratin and sebum balance • Supports healthier scalp microenvironment for hair follicles • Provides overnight regenerative scalp care • Lightweight balm texture designed for prolonged scalp contact • Freshly activated dual-component system for enhanced ingredient stability • Suitable as a complementary maintenance step for professional scalp treatments • Supports scalp recovery following microneedling and energy-based procedures • Formulated with Rose Stem Cell-Derived Extracellular Vesicles (RSCE™), peptides, amino acids, vitamins, and growth factors • Developed by ExoCoBio, the exosome category creator in medical aesthetics

Research, Clinical Tests & Trials Results (Safety & Dermatological)

Clinical evaluations and dermatological testing were conducted by P&K Skin Research Center in South Korea under dermatologist supervision.

After 4 weeks of use, EXOBALM-HR demonstrated measurable improvements in scalp condition and hair-related parameters:

• Hair shedding count decreased by 58% after 4 weeks of application
• Scalp hydration improved by 29%
• Scalp soothing parameters improved by 17%
• Clinically tested for scalp soothing, hydration, keratin balance, scalp oil balance, hair cuticle condition, and reduction of visible hair shedding
• Dermatologically tested for scalp compatibility and sensitive scalp use
• Designed to support scalp recovery and maintenance between professional treatments

The formulation was developed based on ExoCoBio’s regenerative exosome research platform and professional clinical experience with ASCEplus® HRLV, used in aesthetic and regenerative clinics worldwide.

ExoCoBio’s exosome technology platform is supported by:
• 63+ publications
• 75+ patents
• 2.3M+ clinical applications globally
• Clinical presence in 72+ countries

Published literature related to ExoCoBio’s hair exosome technology includes studies involving scalp regeneration, hair repigmentation, exosome-assisted delivery systems, and microneedling combination therapies.

Certifications, Patents & Regulatory Compliance

• Developed by ExoCoBio Inc., the global exosome category creator in medical aesthetics • Backed by 75+ patents related to exosome purification, regenerative applications, and extracellular vesicle technologies • Supported by 63+ scientific publications and ongoing regenerative research programs • Manufactured using ExoCoBio’s proprietary ExoSCRT™ purification technology and ExoGMP™ manufacturing system • Produced under strict GMP manufacturing standards for quality, purity, and consistency • Supported by 2.3M+ clinical applications across 70+ countries worldwide • Professional ASCEplus® protocols used globally in regenerative aesthetic and dermatology clinics • Registered and compliant with major cosmetic regulatory systems including: * US PCPC/ICID * EU CPNP • Dermatologically tested under dermatologist supervision in South Korea • Clinical scalp compatibility and efficacy testing conducted by P&K Skin Research Center

Ingredients List & Formulation (Mandatory, if not specified disqualification from the contest)

Hero Ingredients: • Rosa Damascena Callus Extracellular Vesicles (RSCE™) • Growth Factors & Bioactive Peptides • Copper Tripeptide-1 • Sodium Hyaluronate • Amino Acid Complex • Vitamins & Coenzymes Key Functional Ingredients: • Rose Stem Cell-Derived Extracellular Vesicles (54%) • EGF, IGF-1, FGF, VEGF, PDGF, SCF, Noggin peptides • Biotin • Nicotinamide Adenine Dinucleotide (NAD) • Trehalose • Mannitol • Copper Tripeptide-1 • Sodium Hyaluronate • Amino acids including Lysine, Histidine, Serine, Tryptophan, and Methionine Formulation Features: • Dual-component regenerative scalp system • Lyophilized Exocapsule® technology for ingredient stability • Fresh activation before application • High-purity extracellular vesicle formulation • Overnight scalp recovery balm texture Free-From Claims: • Designed for sensitive scalp compatibility • Dermatologically tested • Developed to minimize scalp irritation while maximizing scalp comfort and hydration

Technology Features

• Dual-component regenerative delivery system separating lyophilized EXO CAPSULE and HCS-FORMULA cream until the moment of use for optimized ingredient freshness and stability • Pharmaceutical-inspired EXO CAPSULE packaging designed to preserve extracellular vesicle integrity and minimize premature ingredient degradation • Single-dose exocapsule format supports hygienic and controlled ingredient activation before application • Transparent jar structure visually highlights the dual-formula architecture and reinforces the product’s regenerative aesthetic identity • Luxury clinical-inspired packaging design combining premium beauty aesthetics with medical regenerative concepts • Color-coded regenerative packaging system uses green for scalp care (HR), blue for skin care (SR), and pink for intimate wellness (WR) for intuitive protocol recognition • Air- and moisture-sensitive lyophilized ingredients protected through sealed capsule pouch structure • Packaging compatibility and durability testing completed, including leakage, drop resistance, immersion stability, temperature resistance, and repeated opening/closing performance testing with PASS results • Jar and capsule components designed for stable storage and minimized contamination risk during repeated use • Integrated spatula mixing concept supports clean and convenient home activation ritual inspired by professional regenerative treatments

Sustainability List of Certifications

• FSC-certified paper packaging components supporting responsible forestry and chain-of-custody sourcing practices • No animal testing (cruelty-free commitment; supporting documentation available upon request) • Produced under cosmetic GMP-compliant manufacturing environments with strict quality and safety standards • Ongoing sustainability initiatives focused on evaluating packaging materials and improving production efficiency to reduce environmental impact • Packaging systems designed to support product stability and minimize unnecessary product waste through freshness-focused delivery structures • Korean packaging material structure evaluation completed with “Excellent Recyclability” rating for packaging components and tray materials by Korea Environment Corporation • Packaging structures designed with separable material components to support improved recycling efficiency • Continuous review of sustainable packaging design, recyclability, and responsible sourcing practices across product development processes • Commitment to balancing luxury regenerative aesthetics with environmentally conscious packaging development

How to use it

• Mix the Exocapsule® with the HCS-Formula™ balm immediately before use •EXOBALM-HR (mixture made from the first and second agent) should be refrigerated. •Apply twice a day (once in the morning, once in the evening); use within 21 days. • Apply evenly onto clean scalp areas of concern • Gently massage to support absorption • Recommended for overnight use for prolonged scalp contact • Suitable for use after professional scalp procedures following practitioner guidance • Can be incorporated into long-term scalp maintenance routines • Recommended for dry, stressed, or sensitive scalp conditions and thinning hair concerns

Market Positioning & Distribution Markets

• Positioning: Premium regenerative scalp homecare inspired by professional aesthetic cosmetics • Distribution Channel: Dermatology clinics, aesthetic clinics, medical spas, professional distributors, premium beauty retail, luxury online beauty platforms • Currently Available In: South Korea, United States, Europe, Middle East, Southeast Asia, Australia, Latin America, and selected global aesthetic markets • Existing Professional Network: Used in regenerative aesthetic clinics across 70+ countries • Target Consumer: Consumers seeking advanced scalp care, post-procedure maintenance, and luxury science-backed hair wellness solutions • Desired Expansion Markets: North America, Europe, Japan, China, Middle East, and premium global scalp care markets • Positioned between professional regenerative treatments and luxury homecare maintenance

Website and/or Social Media Channels + Editorial pitch

Website & Social Media Channels Website: http://www.exocobio.com/ Instagram: https://www.instagram.com/exocobio.official/ Linktree: https://linktr.ee/exocobio?utm_source=linktree_profile_share<sid=55bf2322-1c29-45e9-867b-0a0a2462bbf4 YouTube: https://www.youtube.com/@exocobioinc.7702 Editorial Pitch A dual-phase regenerative scalp balm powered by lyophilized rose stem cell exosomes for intensive hydration and scalp-conditioning care.

Timeline

March 31, 2026

Platform Opening

May 27, 2026

Entries closing

June 22, 2026

Finalists Announcement

July 3, 2026

Deadline for Receiving Products

July 14, 2026

Awards Ceremony
Winners Announcement

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